"The first nanometer resolved image of individual tobacco mosaic virions shows the potential of low-energy electron holography for imaging biomolecules at a single particle level–a milestone in structural biology
“We’ve shown that by means of low-energy holography, it is possible to image individual tobacco mosaic virions deposited on ultraclean freestanding graphene,” said Jean-Nicolas Longchamp, the primary author and a postdoctoral fellow of the Physics Department at the University of Zurich, Switzerland. “The virions are imaged with one nanometer resolution exhibiting details of the helical structure of the virus. Our technique would be the first non-destructive imaging tool for structural biology at the truly single molecule level.”
“Milestone single-biomolecule imaging technique may advance drug design”