There are varying qualities of parallel and serial chipsets, of course; one can Internets themselves some research on that – I’ve found that industrial and test equipment boards tend to have the best discussions on that topic (because they tend to run into the exact same problem as us far more often, and also tend to have very exacting standards for what “good” is in this context).
One other thing I’d note, that I missed from earlier:
Fanless PCs are, as a general rule, designed to not be entirely sealed – for the same reason that they may be quite the opposite of what we’d want in that space. Such PCs are generally designed for living room media center “appliance” use, because such areas will generally have passable airflow and be kept at around room temperature. They didn’t magically find a way around the rule that “heat kills electronics,” sadly. (I wish!)
So a “sealed PC” would tend to have to be pretty over-spec’ed to deal with the levels of heat that would build up within it, and even an “unsealed” fanless PC would not do well in an environment that can get on the hot side. I don’t know for sure, but I get the impression that the Metal Shop may be such an environment – in which case, yes, a fan is yet another potential point of failure and one that would be even more prone to that from little bits of metal floating around, but it may be an inevitable necessity.
Instead of a more “sealed” PC, I’d suggest that the way to mitigate fan issues is to look for a PC that integrates filters in front of its fan bays (or, alternatively, retrofit spacing for filters onto the existing fan bays of whatever we buy #TheMakerWay), and make sure they’re checked and cleaned/replaced on a regular cycle.